Does Hydrocodone/APAP 10/325 keep you up at night?

I have a lot of pain at night so I've been taking the Hydrocodone before I go to bed and it seems to keep me up all night. It feels like I've drank a ton of coffee and can't sleep no matter how tired I am? It's either try to sleep with pain or have less pain and no sleep lol. Has anyone else ever had this problem?


hydrocodone's are a pick me up.. there a pain reliever and a boost to most people. i could see that being the reason you can sleep.. thats why most people sale hydrocodones because people like them because they make pain go away and get your motor running in a other words ha.


Yes, and that's some powerful vicodin. (:

It keeps me up all night as well.


I have taken Hydrocodone before for various reasons and it seems that sometimes it keeps me from sleeping and sometimes it doesn't.

Everybody has their own genetics unique from others.

One type of drug is likely to affect another with common and/or alternate side affects.

Hydrocodone/APAP 10/325 is a mixture of Hydrocodone and Acetaminophen and one of the more potent doses due to the reduced amount of acetaminophen.

So, to answer your question, yes. This drug does keep me up at night sometimes, and sometimes it doesn't. I hope I helped!


I take 2 1/2 of those every 4 hours (broke my back, misdiagnosed so it healed wrong so now i'm in chronic, unending, excruciating pain that the meds hardly even touch ) and I've never had a problem with staying awake. The pills take the sharp edge off the pain but, aside from that, doesn't do much more. It could be something else you're taking that is interacting with the meds. Do you drink any caffine? These pills slow down your digestion so you may be absorbing more of the caffeine for a longer time so it's keeping you up. Aside from that, I don't know. There's no warming on my bottle about keeping you awake, only one about causing drowsiness. Maybe try taking the pill literally right before you lay your head down on the pillow. Hopefully you can fall sleep before it kicks in. if that doesn't work, ask your Dr to let you try another pain medication (stay away from Oxycontin). Good luck.